BA Luther College
PhD Iowa State University
Assistant Professor of Biology Alesia Hruska-Hageman has been teaching full-time at Mount Mercy since 2007. Hruska-Hageman completed undergraduate studies with a Bachelor's degree in biology and art, with a minor in chemistry. She then went on to earn a Doctorate in the Department of Biochemistry, Biophysics, and Molecular Biology with a major in Molecular, Cellular, and Developmental Biology.
After earning her PhD, Hruska-Hageman worked for five years as an Associate of the Howard Hughes Medical Institute in Dr. Michael Welsh's lab at the University of Iowa. Her research focused on the proteins that interact with the Acid Sensing Ion channels which function in learning and memory and our sense of pain and touch. She served as a visiting lecturer at the University of Iowa and as a visiting assistant professor of biology at Coe College. Prior to joining Mount Mercy full-time, she worked part time and taught biochemistry, genetics and microbiology.
Hruska-Hageman has authored many publications and abstracts. She recently started up a research program at Mount Mercy where she works with undergraduate students on protein-protein interactions. Her work focuses on the proteins that interact with PICK1, a protein that binds to receptors involved with learning and memory, axonal growth and cancer.
She is a member of the Iowa Academy of Science, American Association of Cell Biology, and the Council of Undergraduate Research (CUR).
In her spare time, Hruska-Hageman enjoys scrapbooking, gardening, biking and hiking with her family.
Click on magazine cover to read about Dr. Hruska-Hageman's student based research
Excoffon, K. J. D. A, A. O. Kolawole, N. Kusama, N. D. Gansemer, P. Sharma, A. M. Hruska-Hageman, E. Petroff, and C. J. Benson. 2012. Coxsackievirus and adenovirus receptor (CAR) mediates trafficking of acid sensing ion channel 3 (ASIC3) via PSD-95. Biochemical and Biophysical Research Communications 425: 13 – 18. pdf
Ashbourne, K. J. D., A. Hruska-Hageman, M. Klotz, G. L. Traver. 2004. A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growth. Journal of Cell Science 117: 4401-4409. pdf
Leonard, A. S., O. Yermolaieva, A. Hruska-Hageman, C. C. Askwith, M. P. Price, J. A. Wemmie, and M. J. Welsh. 2003. cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1. Proceedings of the National Academy of Sciences 100: 2029 – 2034. pdf
A. M. Hruska-Hageman, C. J. Benson, A. S. Leonard, M. P. Price, and M. J. Welsh. 2004. PSD-25 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+-gated current. Journal of Biological Chemistry 279: 46962 – 46968. pdf
A. M. Hruska-Hageman, J. A. Wemmie, M. P. Price, and M. J. Welsh. 2002. Interactino of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel). Biochemical Journal 361: 443 – 450. pdf